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Read about how researchers in industry
are getting exceptional results using Biosearch Technologies'
products.
Hypusination of eukaryotic initiation factor 5A (eIF5A): a novel therapeutic target in BCR-ABL-positive leukemias identified by a proteomics approach. Balabanov S, Gontarewicz A, Ziegler P, Hartmann U, Kammer W, Copland M, Brassat U, Priemer M, Hauber I, Wilhelm T, Schwarz G, Kanz L, Bokemeyer C, Hauber J, Holyoake TL, Nordheim A, Brümmendorf TH. Blood 2007, 109, 1701–1711.
Optical Antisense Imaging of Tumor with Fluorescent DNA Duplexes Liu, X.; Wang, Y; Nakamura, K; Liu, G; Dou, S; Kubo, A; Rusckowski, M; Hnatowich, D.J. Bioconjugate Chemistry 2007, 18, 1905–1911.
Development and application of a quantitative RT-PCR potency assay for a pentavalent rotavirus vaccine (RotaTeq©) Ranheim, T.; Mathis, P.K.; Joelsson, D.B.; Smith, M.E.; Campbell, K.M.; Lucas, G.; Barmat, S.; Melissen, E.; Benz, R.; Lewis, J.A.; Chen, J.; Schofield, T.; Sitrin, R.D.; Hennessey, J.P. Journal of Virological Methods 2006, 131, 193-201.
2'-Deoxy-2'-Fluoro-á-D-Arabinonucleic Acid (2'F-ANA) Modified Oligonucleotides (ON) Effect Highly Efficient, and Persistent, Gene Silencing Kalota, A.; Karabon, L.; Swider, C.R.; Viazovkina, E.; Elzagheid, M.; Damha, M.J.; Gewirtz, A.M. Nucleic Acids Research. 2006, 34, 451 461.
Sensitive Detection of Human Papillomavirus in Cervical, Head/Neck, and Schistosomiasis-Associated Bladder Malignancies Yang, H.; Yang, K.; Khafagi, A.; Tang, Y.; Carey, T.E.; Opipari, A.W,; Lieberman, R.; Oeth, P.A.; Lancaster, W.; Klinger, HP.; Kaseb, A.O.; Metwally, A.; Khaled, H.; Kurnit, D.M. PNAS 2005, 102, 7683-7688.
Transgenic Rescue Demonstrates Involvement Of The Ian5 Gene In T Cell Development In The Rat Michalkiewicz, M.; Michalkiewicz, T.; Ettinger, R.A.; Rutledge, E.A.; Fuller, J.M.; Moralejo, D.H.; Van Yserloo, B.; MacMurray, A.J.; Kwitek, A.E.; Jacob, H.J.; Lander, E.S.; Lernmark, A. Physiol. Genomics 2004, 19, 228-232.
A Real-Time PCR Assay For DNA-Methylation Using Methylation-Specific Blockers Cottrell, S.E.; Distler, J.; Goodman, N.S., Mooney, S.H.; Kluth, A.; Olek, A.; Schwope, I.; Tetzner, R.; Ziebarth, H.; Berlin, K. Nucl. Acids Res. 2004, 32, e10.
Kin Cohort Estimates For Familial Breast Cancer Risk In Relation To Variants To DNA Base Excision Repair, BRAC1 Interacting And Growth Factor Genes Sigurdson, A.J.; Hauptmann, M.; Chatterjee, N.; Alexander, B.H.; Doody, M.M.; Rutter, J.M.; Struewing, J.P. BMC Cancer 2004, 4, 9.
Attenuation Of Th1 Effector Cell Responses And Susceptibility To Experimental Allergic Encephalomyelitis In Histamine H2 Receptor Knockout Mice Is Due To Dysregulation Of Cytokine Production By Antigen-Presenting Cells Teuscher, C.; Poynter, M.E.; Offner, H.; Zamora, A.; Watanabe, T.; Fillmore, P.D.; Zachary, J.F.; Blankenhorn, E.P. Am. J. Pathol. 2004, 164, 883-892.
Whole Genome Scanning Identifies Genotypes Associated With Recurrence And Metastasis In Prostate Tumors Paris, P.L.; Andaya, A.; Fridlyand, J.; Jain, A.N.; Weinberg, V.; Kowbel, D.; Brebner, J.H.; Simko, J.; Watson, J.E.V.; Volik, S.; Albertson, D.G.; Pinkel, D.; Alers, J.C.; van der Kwast, T.H.; Vissers, K.J.; Schroder, F.H.; Wildhagen, M.F.; Febbo, P.G.; Chinnaiyan, A.M.; Pienta, K.J.; Carroll, P.R.; Rubin, M.A.; Collins, C.; van Dekken, H. Hum. Mol. Genet. 2004, 13, 1303-1313.
Deletion Of Microsomal Prostaglandin E2 (PGE2) Synthase-1 Reduces Inducible And Basal PGE2 Production And Alters The Gastric Prostanoid Profile Boulet, L.; Ouellet, M.; Bateman, K.P.; Ethier, D.; Percival, M.D.; Riendeau, D.; Mancini, J.A.; Methot, N. J. Biol. Chem. 2004, 279, 23229-23237.
Induction Of CYP1A1 In Primary Rat Hepatocytes By 3,3',4,4',5-Pentachlorobiphenyl: Evidence For A Switch Circuit Element French, C.T.; Hanneman, W.H.; Chubb, L.S.; Billings, R.E.; Andersen, M.E. Toxicol. Sci. 2004, 78, 276-286.
Acute Alcohol Inhibits TNF-{Alpha} Processing In Human Monocytes By Inhibiting TNF/TNF-{Alpha}-Converting Enzyme Interactions In The Cell Membrane Zhao, X.; Marrero, L.; Song, K.; Oliver, P.; Chin, S.Y.; Simon, H.; Schurr, J.R.; Zhang, Z.; Thoppil, D.; Lee, S.; Nelson, S.; Kolls, J.K. J. Immunol. 2003, 170, 2923-2931.
Myd88 Primers Macrophages For Full-Scale Activation By Interferon-Gamma Yet Mediates Few Response To Mycobacterium Tuberculosis Shi, S.; Nathan, C.; Schnappinger, D.; Drenkow, J.; Fuortes, M.; Block, E.; Ding, A.; Gingeras, T.R.; Schoolnik, G.; Akira, S.; Takeda, K.; Ehrt, S. J. Exp. Med. 2003, 198, 987-997.
Microsomal Prostaglandin E Synthase-1 Is A Major Terminal Synthase That Is Selectively Up-Regulated During Cyclooxygenase-2-Dependent Prostaglandin E2 Production In The Rat Adjuvant-Induced Arthritis Model Claveau, D.; Sirinyan, M.; Guay, J.; Gordon, R.; Chan, C.; Bureau, Y.; Riendeau, D.; Mancini, J.A. J. Immunol. 2003, 170, 4738-4744.
Development And Clinical Evaluation Of An Internally Controlled, Single-Tube Multiplex Real-Time PCR Assay For Detection Of Legionella Pneumophila And Other Legionella Species Templeton, K.E.; Scheltinga, S.A.; Sillekens, P.; Crielaard, J.W.; van Dam, A.P.; Goossens, H.; Claas, E.C.J. J. Clin. Microbiol. 2003, 41, 4016-4021.
Evaluation Of Real-Time PCR For Detection Of And Discrimination Between Bordetella Pertussis, Bordetella Parapertussis, And Bordetella Holmesii For Clinical Diagnosis Templeton, K.E.; Scheltinga, S.A.; van der Zee, A.; Diederen, B.M.W.; Kruijssen, A.M.; Goossens, H.; Kuijper, E.; Claas, E.C.J. J. Clin. Microbiol. 2003, 41, 4121-4126.
A novel TaqMan real-time PCR assay to estimate ex vivo human immunodeficiency virus type 1 fitness in the era of multi-target (pol and env) antiretroviral therapy Weber, J.; Rangel, H.R.; Chakraborty, B.; Tadele, M.; Martinez, M.A.; Martinez-Picado, J.; Marotta, M.L.; Mirza, M.; Ruiz, L.; Clotet, B.; Wrin, T.; Petropoulos, C.J.; Quinones-Mateu, M.E. J. Gen. Virol. 2003, 84, 2217-2228.
HMGA2 Expression In Uterine Leiomyomata And Myometrium: Quantitative Analysis And Tissue Culture Studies Gross, K.L.; Neskey, D.M.; Manchanda, N.; Weremowicz, S.; Kleinman, M.S.; Nowak, R.A.; Ligon, A.H.; Rogalla, P.; Drechsler, K.; Bullerdiek, J.; Morton, C.C. Genes Chromosomes Cancer 2003, 38, 68-79.
Nerve Growth Factor Blocks The Glucose-Induced Down-Regulation Of Caveolin-1 Expression In Schwann Cells Via P75 Neurotrophin Receptor Signaling Tan, W.; Rouen, S.; Barkus, K.M.; Dremina, Y.S.; Hui, D.; Christianson, J.A.; Wright, D.E.; Yoon, S.O.; Dobrowsky, R.T. J. Biol. Chem. 2003, 278, 23151-23162.
Acute Alcohol Inhibits TNF-{Alpha} Processing In Human Monocytes By Inhibiting TNF/TNF-{Alpha}-Converting Enzyme Interactions In The Cell Membrane Zhao, X.; Marrero, L.; Song, K.; Oliver, P.; Chin, S.Y.; Simon, H.; Schurr, J.R.; Zhang, Z.; Thoppil, D.; Lee, S.; Nelson, S.; Kolls, J.K. J. Immunol. 2003, 170, 2923-2931.
Gene Expression Profiling Reveals Progesterone-Mediated Cell Cycle And Immunoregulatory Roles Of Hoxa-10 In The Preimplantation Uterus Yao, M.W.M.; Lim, H.; Schust, D.J.; Choe, S.E.; Farago, A.; Ding, Y.; Michaud, S.; Church, G.M.; Maas, R.L. Mol. Endocrinol. 2003, 17, 610-627.
A Mutant Epidermal Growth Factor Receptor Targeted To Lung Epithelium Inhibits Asbestos-Induced Proliferation And Proto-Oncogene Expression Manning, C.B.; Cummins, A.B.; Jung, M.W.; Berlanger, I.; Timblin, C.R.; Palmer, C.; Taatjes, D.J.; Hemenway, D.; Vacek, P.; Mossman, B.T. Can. Res. 2002, 62, 4169-4175.
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